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Synthesis of Organosilicon Ligands for Europium (III) and Gadolinium (III) as Potential Imaging Agents

The relaxivity of MRI contrast agents can be increased by increasing the size of the contrast agent and by increasing concentration of the bound gadolinium. Large multi-site ligands able to coordinate several metal centres show increased relaxivity as a result. In this paper, an “aza-type Michael” r...

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Detalles Bibliográficos
Autores principales: Bruce, James I., O’Connell, Patrick J., Taylor, Peter G., Smith, David P.T., Adkin, Roy C., Pearson, Victoria K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570700/
https://www.ncbi.nlm.nih.gov/pubmed/32947960
http://dx.doi.org/10.3390/molecules25184253