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Antisense Oligonucleotides Used to Identify Telomeric G-Quadruplexes in Metaphase Chromosomes and Fixed Cells by Fluorescence Lifetime Imaging Microscopy of o-BMVC Foci

Identification of the existence of G-quadruplex (G4) structure, from a specific G-rich sequence in cells, is critical to the studies of structural biology and drug development. Accumulating evidence supports the existence of G4 structure in vivo. Particularly, time-gated fluorescence lifetime imagin...

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Detalles Bibliográficos
Autores principales: Tseng, Ting-Yuan, Liu, Shin-Ya, Wang, Chiung-Lin, Chang, Ta-Chau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570708/
https://www.ncbi.nlm.nih.gov/pubmed/32906697
http://dx.doi.org/10.3390/molecules25184083