The Reactions of H(2)O(2) and GSNO with the Zinc Finger Motif of XPA. Not A Regulatory Mechanism, But No Synergy with Cadmium Toxicity

Tetrathiolate zinc fingers are potential targets of oxidative assault under cellular stress conditions. We used the synthetic 37-residue peptide representing the tetrathiolate zinc finger domain of the DNA repair protein XPA, acetyl-DYVICEECGKEFMSYLMNHFDLPTCDNCRDADDKHK-amide (XPAzf) as a working mod...

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Detalles Bibliográficos
Autores principales: Witkiewicz-Kucharczyk, Aleksandra, Goch, Wojciech, Olędzki, Jacek, Hartwig, Andrea, Bal, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570819/
https://www.ncbi.nlm.nih.gov/pubmed/32932594
http://dx.doi.org/10.3390/molecules25184177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570819/
https://www.ncbi.nlm.nih.gov/pubmed/32932594
http://dx.doi.org/10.3390/molecules25184177

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