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Ruthenium(II)/(III) DMSO-Based Complexes of 2-Aminophenyl Benzimidazole with In Vitro and In Vivo Anticancer Activity

New anticancer ruthenium(II/III) complexes [RuCl(2)(DMSO)(2)(Hapbim)] (1) and [RuCl(3)(DMSO) (Hapbim)] (2) (Hapbim = 2-aminophenyl benzimidazole) have been synthesized and characterized, and their chemotherapeutic potential evaluated. The interaction of the compounds with DNA was studied by both UV-...

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Detalles Bibliográficos
Autores principales: Elsayed, Shadia A., Harrypersad, Shane, Sahyon, Heba A., El-Magd, Mohammed Abu, Walsby, Charles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570852/
https://www.ncbi.nlm.nih.gov/pubmed/32962014
http://dx.doi.org/10.3390/molecules25184284