Cytotoxicity of Oleandrin Is Mediated by Calcium Influx and by Increased Manganese Uptake in Saccharomyces cerevisiae Cells

Oleandrin, the main component of Nerium oleander L. extracts, is a cardiotoxic glycoside with multiple pharmacological implications, having potential anti-tumoral and antiviral characteristics. Although it is accepted that the main mechanism of oleandrin action is the inhibition of Na(+)/K(+)-ATPase...

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Detalles Bibliográficos
Autores principales: Ruta, Lavinia L., Popa, Claudia V., Farcasanu, Ileana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570853/
https://www.ncbi.nlm.nih.gov/pubmed/32957533
http://dx.doi.org/10.3390/molecules25184259

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570853/
https://www.ncbi.nlm.nih.gov/pubmed/32957533
http://dx.doi.org/10.3390/molecules25184259

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