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Downregulation of Inflammatory Cytokine Release from IL-1β and LPS-Stimulated PBMC Orchestrated by ST2825, a MyD88 Dimerisation Inhibitor

The inflammatory process implicates homeostasis disruption and increased production of inflammatory mediators. Myeloid differentiation primary response 88 (MyD88) is an essential protein recruited after lipopolysaccharide (LPS) and interleukin (IL)-1β stimulation, a process that converges in nuclear...

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Detalles Bibliográficos
Autores principales: Ramírez-Pérez, Sergio, Hernández-Palma, Luis Alexis, Oregon-Romero, Edith, Anaya-Macías, Brian Uriel, García-Arellano, Samuel, González-Estevez, Guillermo, Muñoz-Valle, José Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570868/
https://www.ncbi.nlm.nih.gov/pubmed/32967164
http://dx.doi.org/10.3390/molecules25184322