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Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies—Present State, Challenges, and Perspectives

Cardiac arrhythmias are serious, life-threatening diseases associated with the dysregulation of Ca [Formula: see text] influx into the cytoplasm of cardiomyocytes. This dysregulation often arises from dysfunction of ryanodine receptor 2 (RyR2), the principal Ca [Formula: see text] release channel. D...

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Detalles Bibliográficos
Autores principales: Bauerová-Hlinková, Vladena, Hajdúchová, Dominika, Bauer, Jacob A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570887/
https://www.ncbi.nlm.nih.gov/pubmed/32899693
http://dx.doi.org/10.3390/molecules25184040