Cathepsin B-Cleavable Cyclopeptidic Chemotherapeutic Prodrugs

Cyclopeptidic chemotherapeutic prodrugs (cPCPs) are macromolecular protease-sensitive doxorubicin (DOX) prodrugs synthesized from a cyclodecapeptidic scaffold, termed Regioselectively Addressable Functionalized Template (RAFT). In order to increase the chemotherapeutic potential of DOX and limit its...

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Detalles Bibliográficos
Autores principales: Herceg, Viktorija, Bouilloux, Jordan, Janikowska, Karolina, Allémann, Eric, Lange, Norbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570921/
https://www.ncbi.nlm.nih.gov/pubmed/32962018
http://dx.doi.org/10.3390/molecules25184285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570921/
https://www.ncbi.nlm.nih.gov/pubmed/32962018
http://dx.doi.org/10.3390/molecules25184285

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