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Cathepsin B-Cleavable Cyclopeptidic Chemotherapeutic Prodrugs

Cyclopeptidic chemotherapeutic prodrugs (cPCPs) are macromolecular protease-sensitive doxorubicin (DOX) prodrugs synthesized from a cyclodecapeptidic scaffold, termed Regioselectively Addressable Functionalized Template (RAFT). In order to increase the chemotherapeutic potential of DOX and limit its...

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Detalles Bibliográficos
Autores principales:	Herceg, Viktorija, Bouilloux, Jordan, Janikowska, Karolina, Allémann, Eric, Lange, Norbert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570921/ https://www.ncbi.nlm.nih.gov/pubmed/32962018 http://dx.doi.org/10.3390/molecules25184285

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