Identification of Potential COX-2 Inhibitors for the Treatment of Inflammatory Diseases Using Molecular Modeling Approaches

Non-steroidal anti-inflammatory drugs are inhibitors of cyclooxygenase-2 (COX-2) that were developed in order to avoid the side effects of non-selective inhibitors of COX-1. Thus, the present study aims to identify new selective chemical entities for the COX-2 enzyme via molecular modeling approache...

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Detalles Bibliográficos
Autores principales: Araújo, Pedro H. F., Ramos, Ryan S., da Cruz, Jorddy N., Silva, Sebastião G., Ferreira, Elenilze F. B., de Lima, Lúcio R., Macêdo, Williams J. C., Espejo-Román, José M., Campos, Joaquín M., Santos, Cleydson B. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570943/
https://www.ncbi.nlm.nih.gov/pubmed/32932669
http://dx.doi.org/10.3390/molecules25184183

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570943/
https://www.ncbi.nlm.nih.gov/pubmed/32932669
http://dx.doi.org/10.3390/molecules25184183

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