Synthesis of Novel 2-(Isopropylamino)thiazol-4(5H)-one Derivatives and Their Inhibitory Activity of 11β-HSD1 and 11β-HSD2 in Aspect of Carcinogenesis Prevention

Glucocorticoid metabolism at the tissue level is regulated by two isoenzymes 11β-hydroxysteroid dehydrogenase (11β-HSD), which mutually convert biologically active cortisol and inactive cortisone. Recent research is focused on the role of 11β-HSD1 and 11β-HSD2 as autocrine factors of tumor cell prol...

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Detalles Bibliográficos
Autores principales: Kupczyk, Daria, Studzińska, Renata, Bilski, Rafał, Baumgart, Szymon, Kołodziejska, Renata, Woźniak, Alina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570983/
https://www.ncbi.nlm.nih.gov/pubmed/32942682
http://dx.doi.org/10.3390/molecules25184233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7570983/
https://www.ncbi.nlm.nih.gov/pubmed/32942682
http://dx.doi.org/10.3390/molecules25184233

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