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Effect of Molecular Crowding on DNA Polymerase Reactions along Unnatural DNA Templates

Unnatural nucleic acids are promising materials to expand genetic information beyond the natural bases. During replication, substrate nucleotide incorporation should be strictly controlled for optimal base pairing with template strand bases. Base-pairing interactions occur via hydrogen bonding and b...

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Detalles Bibliográficos
Autores principales: Takahashi, Shuntaro, Herdwijn, Piet, Sugimoto, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571040/
https://www.ncbi.nlm.nih.gov/pubmed/32927591
http://dx.doi.org/10.3390/molecules25184120