Design, Synthesis, In Vitro and In Silico Studies of New Thiazolylhydrazine-Piperazine Derivatives as Selective MAO-A Inhibitors

Monoamine oxidase (MAO) isoenzymes are very important drug targets among neurological disorders. Herein, novel series of thiazolylhydrazine-piperazine derivatives were designed, synthesized and evaluated for their MAO-A and -B inhibitory activity. The structures of the synthesized compounds were ass...

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Detalles Bibliográficos
Autores principales: Sağlık, Begüm Nurpelin, Cebeci, Osman, Acar Çevik, Ulviye, Osmaniye, Derya, Levent, Serkan, Kaya Çavuşoğlu, Betül, Ilgın, Sinem, Özkay, Yusuf, Kaplancıklı, Zafer Asım
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571065/
https://www.ncbi.nlm.nih.gov/pubmed/32971892
http://dx.doi.org/10.3390/molecules25184342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571065/
https://www.ncbi.nlm.nih.gov/pubmed/32971892
http://dx.doi.org/10.3390/molecules25184342

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