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Five Novel Non-Sialic Acid-Like Scaffolds Inhibit In Vitro H1N1 and H5N2 Neuraminidase Activity of Influenza a Virus

Neuraminidase (NA) of influenza viruses enables the virus to access the cell membrane. It degrades the sialic acid contained in extracellular mucin. Later, it is responsible for releasing newly formed virions from the membrane of infected cells. Both processes become key functions within the viral c...

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Detalles Bibliográficos
Autores principales: Márquez-Domínguez, Luis, Reyes-Leyva, Julio, Herrera-Camacho, Irma, Santos-López, Gerardo, Scior, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571124/
https://www.ncbi.nlm.nih.gov/pubmed/32947893
http://dx.doi.org/10.3390/molecules25184248