Identification of Novel Src Inhibitors: Pharmacophore-Based Virtual Screening, Molecular Docking and Molecular Dynamics Simulations

Src plays a crucial role in many signaling pathways and contributes to a variety of cancers. Therefore, Src has long been considered an attractive drug target in oncology. However, the development of Src inhibitors with selectivity and novelty has been challenging. In the present study, pharmacophor...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Zhang, Ting-jian, Tu, Shun, Zhang, Zhen-hao, Meng, Fan-hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571137/
https://www.ncbi.nlm.nih.gov/pubmed/32911607
http://dx.doi.org/10.3390/molecules25184094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571137/
https://www.ncbi.nlm.nih.gov/pubmed/32911607
http://dx.doi.org/10.3390/molecules25184094

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