Multistep Synthesis and In Vitro Anticancer Evaluation of 2-Pyrazolyl-Estradiol Derivatives, Pyrazolocoumarin-Estradiol Hybrids and Analogous Compounds

Although the hormone independent cytotoxic activity of several estradiol derivatives endowed with a simple substituent at C-2 has been reported so far, 2-heterocyclic and 2,3-condensed analogs are less investigated from both synthetic and pharmacological points of view. Therefore, novel A-ring-conne...

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Detalles Bibliográficos
Autores principales: Molnár, Barnabás, Gopisetty, Mohana Krishna, Adamecz, Dóra Izabella, Kiricsi, Mónika, Frank, Éva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571145/
https://www.ncbi.nlm.nih.gov/pubmed/32899643
http://dx.doi.org/10.3390/molecules25184039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571145/
https://www.ncbi.nlm.nih.gov/pubmed/32899643
http://dx.doi.org/10.3390/molecules25184039

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