Design, Synthesis and Biological Investigation of Flavone Derivatives as Potential Multi-Receptor Atypical Antipsychotics

The design of a series of novel flavone derivatives was synthesized as potential broad-spectrum antipsychotics by using multi-receptor affinity strategy between dopamine receptors and serotonin receptors. Among them, 7-(4-(4-(6-fluorobenzo[d]isoxazol-3-yl) piperidin- 1-yl) butoxy)-2,2-dimethylchroma...

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Detalles Bibliográficos
Autores principales: Gao, Lanchang, Yang, Zhengge, Xiong, Jiaying, Hao, Chao, Ma, Ru, Liu, Xin, Liu, Bi-Feng, Jin, Jian, Zhang, Guisen, Chen, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571155/
https://www.ncbi.nlm.nih.gov/pubmed/32911828
http://dx.doi.org/10.3390/molecules25184107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571155/
https://www.ncbi.nlm.nih.gov/pubmed/32911828
http://dx.doi.org/10.3390/molecules25184107

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