Novel Acetylcholinesterase Inhibitors Based on Uracil Moiety for Possible Treatment of Alzheimer Disease

In this study, novel derivatives based on 6-methyluracil and condensed uracil were synthesized, namely, 2,4-quinazoline-2,4-dione with ω-(ortho-nitrilebenzylethylamino) alkyl chains at the N atoms of the pyrimidine ring. In this series of synthesized compounds, the polymethylene chains were varied f...

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Detalles Bibliográficos
Autores principales: Semenov, Vyacheslav E., Zueva, Irina V., Mukhamedyarov, Marat A., Lushchekina, Sofya V., Petukhova, Elena O., Gubaidullina, Lilya M., Krylova, Evgeniya S., Saifina, Lilya F., Lenina, Oksana A., Petrov, Konstantin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571187/
https://www.ncbi.nlm.nih.gov/pubmed/32932702
http://dx.doi.org/10.3390/molecules25184191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571187/
https://www.ncbi.nlm.nih.gov/pubmed/32932702
http://dx.doi.org/10.3390/molecules25184191

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