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Novel Acetylcholinesterase Inhibitors Based on Uracil Moiety for Possible Treatment of Alzheimer Disease
In this study, novel derivatives based on 6-methyluracil and condensed uracil were synthesized, namely, 2,4-quinazoline-2,4-dione with ω-(ortho-nitrilebenzylethylamino) alkyl chains at the N atoms of the pyrimidine ring. In this series of synthesized compounds, the polymethylene chains were varied f...
Autores principales: | Semenov, Vyacheslav E., Zueva, Irina V., Mukhamedyarov, Marat A., Lushchekina, Sofya V., Petukhova, Elena O., Gubaidullina, Lilya M., Krylova, Evgeniya S., Saifina, Lilya F., Lenina, Oksana A., Petrov, Konstantin A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571187/ https://www.ncbi.nlm.nih.gov/pubmed/32932702 http://dx.doi.org/10.3390/molecules25184191 |
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