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A Novel Cytotoxic Conjugate Derived from the Natural Product Podophyllotoxin as a Direct-Target Protein Dual Inhibitor

Natural products are the ideal basis for the design of novel efficient molecular entities. Podophyllotoxin, a naturally occurring cyclolignan, is an example of natural product which displays a high versatility from a biological activity point of view. Based on its unique chemical structure, differen...

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Detalles Bibliográficos
Autores principales: Hernández, Ángela-Patricia, Díez, Paula, García, Pablo A., Pérez-Andrés, Martín, Ortega, Pablo, Jambrina, Pablo G., Díez, David, Castro, María Ángeles, Fuentes, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571232/
https://www.ncbi.nlm.nih.gov/pubmed/32957517
http://dx.doi.org/10.3390/molecules25184258