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A Novel Cytotoxic Conjugate Derived from the Natural Product Podophyllotoxin as a Direct-Target Protein Dual Inhibitor
Natural products are the ideal basis for the design of novel efficient molecular entities. Podophyllotoxin, a naturally occurring cyclolignan, is an example of natural product which displays a high versatility from a biological activity point of view. Based on its unique chemical structure, differen...
Autores principales: | Hernández, Ángela-Patricia, Díez, Paula, García, Pablo A., Pérez-Andrés, Martín, Ortega, Pablo, Jambrina, Pablo G., Díez, David, Castro, María Ángeles, Fuentes, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571232/ https://www.ncbi.nlm.nih.gov/pubmed/32957517 http://dx.doi.org/10.3390/molecules25184258 |
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