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Synthesis of Fucose Derivatives with Thiol Motifs towards Suicide Inhibition of Helicobacter pylori

The syntheses of six thiol-exhibiting monosaccharides towards suicide inhibition of Helicobacter pylori are reported. Blood group Antigen Binding Adhesin (BabA), a bacterial membrane-bound lectin, binds to human ABO and Lewis b blood group structures displayed on the surface of host epithelial cells...

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Detalles Bibliográficos
Autores principales: Reihill, Mark, Guazzelli, Lorenzo, Remaut, Han, Oscarson, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571248/
https://www.ncbi.nlm.nih.gov/pubmed/32961972
http://dx.doi.org/10.3390/molecules25184281