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Treatment Efficacy and Biocompatibility of a Biodegradable Aflibercept-Loaded Microsphere-Hydrogel Drug Delivery System

PURPOSE: To evaluate the in vivo treatment efficacy and biocompatibility of a biodegradable aflibercept-loaded microsphere-hydrogel drug delivery system (DDS) in a laser-induced choroidal neovascularization (CNV) rat model. METHODS: Two weeks after CNV induction, animals were randomly assigned into...

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Detalles Bibliográficos
Autores principales: Liu, Wenqiang, Tawakol, Anessa Puskar, Rudeen, Kayla M., Mieler, William F., Kang-Mieler, Jennifer J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571288/
https://www.ncbi.nlm.nih.gov/pubmed/33117605
http://dx.doi.org/10.1167/tvst.9.11.13