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Targeting lactate dehydrogenase A (LDHA) exerts antileukemic effects on T‐cell acute lymphoblastic leukemia

BACKGROUND: T‐cell acute lymphoblastic leukemia (T‐ALL) is an uncommon and aggressive subtype of acute lymphoblastic leukemia (ALL). In the serum of T‐ALL patients, the activity of lactate dehydrogenase A (LDHA) is increased. We proposed that targeting LDHA may be a potential strategy to improve T‐A...

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Detalles Bibliográficos
Autores principales: Yu, Haizhi, Yin, Yafei, Yi, Yifang, Cheng, Zhao, Kuang, Wenyong, Li, Ruijuan, Zhong, Haiying, Cui, Yajuan, Yuan, Lingli, Gong, Fanjie, Wang, Zhihua, Li, Heng, Peng, Hongling, Zhang, Guangsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571401/
https://www.ncbi.nlm.nih.gov/pubmed/32820611
http://dx.doi.org/10.1002/cac2.12080