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T‐cell receptor repertoire analysis for the diagnosis and treatment of solid tumor: A methodology and clinical applications

T cells, which are involved in adaptive immunity, are essential in the elimination of tumor cells. Mature T cells can specifically recognize the antigen on the major histocompatibility complex (MHC) molecule through T‐cell receptors (TCR). The unique rearrangement mechanisms during T‐cell maturation...

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Detalles Bibliográficos
Autores principales: Li, Na, Yuan, Jiani, Tian, Wenjia, Meng, Lin, Liu, Yongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571402/
https://www.ncbi.nlm.nih.gov/pubmed/32677768
http://dx.doi.org/10.1002/cac2.12074