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Mifepristone as a Potential Therapy to Reduce Angiogenesis and P-Glycoprotein Associated With Glioblastoma Resistance to Temozolomide

Glioblastoma, the most common primary central nervous system tumor, is characterized by extensive vascular neoformation and an area of necrosis generated by rapid proliferation. The standard treatment for this type of tumor is surgery followed by chemotherapy based on temozolomide and radiotherapy,...

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Detalles Bibliográficos
Autores principales: Llaguno-Munive, Monserrat, León-Zetina, Sebastián, Vazquez-Lopez, Inés, Ramos-Godinez, María del Pilar, Medina, Luis A., Garcia-Lopez, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571516/
https://www.ncbi.nlm.nih.gov/pubmed/33123485
http://dx.doi.org/10.3389/fonc.2020.581814