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Chronic HIV-1 Tat exposure alters anterior cingulate cortico-basal ganglia-thalamocortical synaptic circuitry, associated behavioral control, and immune regulation in male mice

HIV-1 selectively disrupts neuronal integrity within specific brain regions, reflecting differences in viral tropism and/or the regional differences in the vulnerability of distinct neuronal subpopulations within the CNS. Deficits in prefrontal cortex (PFC)-mediated executive function and the result...

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Detalles Bibliográficos
Autores principales: Nass, Sara R., Hahn, Yun K., McLane, Virginia D., Varshneya, Neil B., Damaj, M. Imad, Knapp, Pamela E., Hauser, Kurt F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571616/
https://www.ncbi.nlm.nih.gov/pubmed/33083793
http://dx.doi.org/10.1016/j.bbih.2020.100077