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PCNA antagonizes cohesin-dependent roles in genomic stability

PCNA sliding clamp binds factors through which histone deposition, chromatin remodeling, and DNA repair are coupled to DNA replication. PCNA also directly binds Eco1/Ctf7 acetyltransferase, which in turn activates cohesins and establishes cohesion between nascent sister chromatids. While increased r...

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Detalles Bibliográficos
Autores principales: Zuilkoski, Caitlin M., Skibbens, Robert V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571713/
https://www.ncbi.nlm.nih.gov/pubmed/33075068
http://dx.doi.org/10.1371/journal.pone.0235103