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Which patients to sample in clinical cohort studies when the number of events is high and measurement of additional markers is constrained by limited resources

PURPOSE: We consider an existing clinical cohort with events but limited resources for the investigation of a further potentially expensive marker. Biological material of the patients is stored in a biobank, but only a limited number of samples can be analyzed with respect to the marker. The questio...

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Detalles Bibliográficos
Autores principales: Edelmann, Dominic, Ohneberg, Kristin, Becker, Natalia, Benner, Axel, Schumacher, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571814/
https://www.ncbi.nlm.nih.gov/pubmed/32813923
http://dx.doi.org/10.1002/cam4.3381