EBV‐LMP1 induces APOBEC3s and mitochondrial DNA hypermutation in nasopharyngeal cancer

An Epstein‐Barr virus (EBV)—encoded latent membrane protein 1 (LMP1) is a principal oncogene that plays a pivotal role in EBV‐associated malignant tumors including nasopharyngeal cancer (NPC). Recent genomic landscape studies revealed that NPC also contained many genomic mutations, suggesting the ro...

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Detalles Bibliográficos
Autores principales: Wakae, Kousho, Kondo, Satoru, Pham, Hai Thanh, Wakisaka, Naohiro, Que, Lusheng, Li, Yingfang, Zheng, Xin, Fukano, Kento, Kitamura, Kouichi, Watashi, Koichi, Aizaki, Hideki, Ueno, Takayoshi, Moriyama‐Kita, Makiko, Ishikawa, Kazuya, Nakanishi, Yosuke, Endo, Kazuhira, Muramatsu, Masamichi, Yoshizaki, Tomokazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571841/
https://www.ncbi.nlm.nih.gov/pubmed/32815637
http://dx.doi.org/10.1002/cam4.3357

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7571841/
https://www.ncbi.nlm.nih.gov/pubmed/32815637
http://dx.doi.org/10.1002/cam4.3357

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