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Single-cell transcriptomics identifies divergent developmental lineage trajectories during human pituitary development

The anterior pituitary gland plays a central role in regulating various physiological processes, including body growth, reproduction, metabolism and stress response. Here, we perform single-cell RNA-sequencing (scRNA-seq) of 4113 individual cells from human fetal pituitaries. We characterize diverge...

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Detalles Bibliográficos
Autores principales: Zhang, Shu, Cui, Yueli, Ma, Xinyi, Yong, Jun, Yan, Liying, Yang, Ming, Ren, Jie, Tang, Fuchou, Wen, Lu, Qiao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572359/
https://www.ncbi.nlm.nih.gov/pubmed/33077725
http://dx.doi.org/10.1038/s41467-020-19012-4