Cytoskeletal disorganization underlies PABPN1-mediated myogenic disability

Muscle wasting and atrophy are regulated by multiple molecular processes, including mRNA processing. Reduced levels of the polyadenylation binding protein nucleus 1 (PABPN1), a multifactorial regulator of mRNA processing, cause muscle atrophy. A proteomic study in muscles with reduced PABPN1 levels...

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Detalles Bibliográficos
Autores principales: Olie, Cyriel Sebastiaan, van der Wal, Erik, Cikes, Domagoj, Maton, Loes, de Greef, Jessica C., Lin, I.-Hsuan, Chen, Yi-Fan, Kareem, Elsayad, Penninger, Josef M., Kessler, Benedikt M., Raz, Vered
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572364/
https://www.ncbi.nlm.nih.gov/pubmed/33077830
http://dx.doi.org/10.1038/s41598-020-74676-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572364/
https://www.ncbi.nlm.nih.gov/pubmed/33077830
http://dx.doi.org/10.1038/s41598-020-74676-8

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