HLA-A alleles including HLA-A29 affect the composition of the gut microbiome: a potential clue to the pathogenesis of birdshot retinochoroidopathy

Birdshot retinochoroidopathy occurs exclusively in individuals who are HLA-A29 positive. The mechanism to account for this association is unknown. The gut microbiome has been causally implicated in many immune-mediated diseases. We hypothesized that HLA-A29 would affect the composition of the gut mi...

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Detalles Bibliográficos
Autores principales: Sternes, Peter R., Martin, Tammy M., Paley, Michael, Diamond, Sarah, Asquith, Mark J., Brown, Matthew A., Rosenbaum, James T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572371/
https://www.ncbi.nlm.nih.gov/pubmed/33077849
http://dx.doi.org/10.1038/s41598-020-74751-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572371/
https://www.ncbi.nlm.nih.gov/pubmed/33077849
http://dx.doi.org/10.1038/s41598-020-74751-0

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