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HLA-A alleles including HLA-A29 affect the composition of the gut microbiome: a potential clue to the pathogenesis of birdshot retinochoroidopathy
Birdshot retinochoroidopathy occurs exclusively in individuals who are HLA-A29 positive. The mechanism to account for this association is unknown. The gut microbiome has been causally implicated in many immune-mediated diseases. We hypothesized that HLA-A29 would affect the composition of the gut mi...
Autores principales: | Sternes, Peter R., Martin, Tammy M., Paley, Michael, Diamond, Sarah, Asquith, Mark J., Brown, Matthew A., Rosenbaum, James T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572371/ https://www.ncbi.nlm.nih.gov/pubmed/33077849 http://dx.doi.org/10.1038/s41598-020-74751-0 |
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