Novel approach to quantify mitochondrial content and intrinsic bioenergetic efficiency across organs

Human disease pathophysiology commonly involves metabolic disruption at both the cellular and subcellular levels. Isolated mitochondria are a powerful model for separating global cellular changes from intrinsic mitochondrial alterations. However, common laboratory practices for isolating mitochondri...

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Detalles Bibliográficos
Autores principales: McLaughlin, Kelsey L., Hagen, James T., Coalson, Hannah S., Nelson, Margaret A. M., Kew, Kimberly A., Wooten, Ashley R., Fisher-Wellman, Kelsey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572412/
https://www.ncbi.nlm.nih.gov/pubmed/33077793
http://dx.doi.org/10.1038/s41598-020-74718-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572412/
https://www.ncbi.nlm.nih.gov/pubmed/33077793
http://dx.doi.org/10.1038/s41598-020-74718-1

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