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[(11)C]PIB amyloid quantification: effect of reference region selection

BACKGROUND: The standard reference region (RR) for amyloid-beta (Aβ) PET studies is the cerebellar grey matter (GMCB), while alternative RRs have mostly been utilized without prior validation against the gold standard. This study compared five commonly used RRs to gold standard plasma input-based qu...

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Detalles Bibliográficos
Autores principales: Heeman, Fiona, Hendriks, Janine, Lopes Alves, Isadora, Ossenkoppele, Rik, Tolboom, Nelleke, van Berckel, Bart N. M., Lammertsma, Adriaan A., Yaqub, Maqsood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7572969/
https://www.ncbi.nlm.nih.gov/pubmed/33074395
http://dx.doi.org/10.1186/s13550-020-00714-1