hnRNPH2 as an Inhibitor of Chicken MDA5-Mediated Type I Interferon Response: Analysis Using Chicken MDA5–Host Interactome

RIG-I and MDA5 are two key pattern recognition receptors that sense the invasion of RNA viruses and initiate type I interferon (IFN) response. Although these receptors are generally conserved in vertebrates, RIG-I is absent in chickens, whereas MDA5 is present. Chicken MDA5 (chMDA5) plays a pivotal...

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Detalles Bibliográficos
Autores principales: Lin, Xian, Yu, Shiman, Mao, Haiying, Ren, Peilei, Jin, Meilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573076/
https://www.ncbi.nlm.nih.gov/pubmed/33123126
http://dx.doi.org/10.3389/fimmu.2020.541267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573076/
https://www.ncbi.nlm.nih.gov/pubmed/33123126
http://dx.doi.org/10.3389/fimmu.2020.541267

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