Effect of AKT1 (p. E17K) Hotspot Mutation on Malignant Tumorigenesis and Prognosis

The substitution of the seventeenth amino acid glutamate by lysine in the homologous structural domain of the Akt1 gene pleckstrin is a somatic cellular mutation found in breast, colorectal, and ovarian cancers, named p. Glu17Lys or E17K. In recent years, a growing number of studies have suggested t...

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Detalles Bibliográficos
Autores principales: Chen, Ying, Huang, Lan, Dong, Yongjian, Tao, Changli, Zhang, Rongxin, Shao, Hongwei, Shen, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573235/
https://www.ncbi.nlm.nih.gov/pubmed/33123537
http://dx.doi.org/10.3389/fcell.2020.573599

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573235/
https://www.ncbi.nlm.nih.gov/pubmed/33123537
http://dx.doi.org/10.3389/fcell.2020.573599

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