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P2X7 Receptor Upregulation in Huntington’s Disease Brains

Huntington’s disease (HD) is a fatal degenerative disorder affecting the nervous system. It is characterized by motor, cognitive, and psychiatric dysfunctions, with a late onset and an autosomal dominant pattern of inheritance. HD-causing mutation consists in an expansion of repeated CAG triplets in...

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Detalles Bibliográficos
Autores principales: Ollà, Ivana, Santos-Galindo, María, Elorza, Ainara, Lucas, José J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573237/
https://www.ncbi.nlm.nih.gov/pubmed/33122998
http://dx.doi.org/10.3389/fnmol.2020.567430