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Novel TrxR1 Inhibitors Show Potential for Glioma Treatment by Suppressing the Invasion and Sensitizing Glioma Cells to Chemotherapy

Currently, available glioblastoma (GBM) treatment remains ineffective, with relapse after initial response and low survival rate of GBM patients. The reasons behind limited capacities for GBM treatment are high tumor heterogeneity, invasiveness, and occurrence of drug resistance. Therefore, developi...

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Detalles Bibliográficos
Autores principales: Jovanović, Mirna, Dragoj, Miodrag, Zhukovsky, Daniil, Dar’in, Dmitry, Krasavin, Mikhail, Pešić, Milica, Podolski-Renić, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573255/
https://www.ncbi.nlm.nih.gov/pubmed/33134322
http://dx.doi.org/10.3389/fmolb.2020.586146