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FMN riboswitch aptamer symmetry facilitates conformational switching through mutually exclusive coaxial stacking configurations

Knowledge of both apo and holo states of riboswitches aid in elucidating the various mechanisms of ligand-induced conformational “switching” that underpin their gene-regulating capabilities. Previous structural studies on the flavin mononucleotide (FMN)-binding aptamer of the FMN riboswitch, however...

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Detalles Bibliográficos
Autores principales: Wilt, Haley M., Yu, Ping, Tan, Kemin, Wang, Yun-Xing, Stagno, Jason R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573352/
https://www.ncbi.nlm.nih.gov/pubmed/33103111
http://dx.doi.org/10.1016/j.yjsbx.2020.100035