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FMN riboswitch aptamer symmetry facilitates conformational switching through mutually exclusive coaxial stacking configurations
Knowledge of both apo and holo states of riboswitches aid in elucidating the various mechanisms of ligand-induced conformational “switching” that underpin their gene-regulating capabilities. Previous structural studies on the flavin mononucleotide (FMN)-binding aptamer of the FMN riboswitch, however...
Autores principales: | Wilt, Haley M., Yu, Ping, Tan, Kemin, Wang, Yun-Xing, Stagno, Jason R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573352/ https://www.ncbi.nlm.nih.gov/pubmed/33103111 http://dx.doi.org/10.1016/j.yjsbx.2020.100035 |
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