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Characterization of the 5′-flanking region of the human and mouse CHAC1 genes

The Unfolded Protein Response pathway is a conserved signaling mechanism having important roles in cellular physiology and is perturbed accompanying disease. We previously identified the novel UPR target gene CHAC1, a direct target of ATF4, downstream of PERK-EIF2A and activated by the UPR pathway....

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Detalles Bibliográficos
Autores principales: Nomura, Yuki, Sylvester, Charity F., Nguyen, Lisa O., Kandeel, Mahmoud, Hirata, Yoko, Mungrue, Imran N., Oh-hashi, Kentaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573368/
https://www.ncbi.nlm.nih.gov/pubmed/33102815
http://dx.doi.org/10.1016/j.bbrep.2020.100834