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Practical Laboratory Tools for Monitoring of BCR-ABL1 Transcripts and Tyrosine Kinase (TK) Domain Mutations in Chronic Myeloid Leukemia Patients Undergoing TK Inhibitor Therapy: A Single-Center Experience in Thailand

OBJECTIVE: The genetic hallmark of CML is known as the appearance of t(9;22)(q34.1;q11.2) (BCR-ABL1) which is present in more than 95% of cases. Here, we demonstrated practical laboratory tools for monitoring of BCR-ABL1 transcripts in chronic myeloid leukemia patients undergoing TK inhibitor therap...

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Detalles Bibliográficos
Autores principales: Limsuwanachot, Nittaya, Kongruang, Adcharee, Rerkamnuaychoke, Budsaba, Singdong, Roongrudee, Niparuck, Pimjai, Jootar, Saengsuree, Siriboonpiputtana, Teerapong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573403/
https://www.ncbi.nlm.nih.gov/pubmed/32711426
http://dx.doi.org/10.31557/APJCP.2020.21.7.2003