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NOTCH-1 Gene Mutations Influence Survival in Acute Myeloid Leukemia Patients

BACKGROUND: Although NOTCH-1 gene mutations were reported to contributes to leukemogenesis in lymphocytic leukemias, its role in acute myeloid leukemia (AML) remains unclear. Therefor; this study was designed to determine the prevalence and clinical impact of NOTCH-1 mutations in AML patients. MATER...

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Detalles Bibliográficos
Autores principales: Aref, Salah, Rizk, Rasha, El Agdar, Mohamed, Fakhry, Wafaa, El Zafrany, Maha, Sabry, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573420/
https://www.ncbi.nlm.nih.gov/pubmed/32711424
http://dx.doi.org/10.31557/APJCP.2020.21.7.1987