Increased Plasma Heparanase Activity in COVID-19 Patients

Reports suggest a role of endothelial dysfunction and loss of endothelial barrier function in COVID-19. It is well established that the endothelial glycocalyx-degrading enzyme heparanase contributes to vascular leakage and inflammation. Low molecular weight heparins (LMWH) serve as an inhibitor of h...

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Detalles Bibliográficos
Autores principales: Buijsers, Baranca, Yanginlar, Cansu, de Nooijer, Aline, Grondman, Inge, Maciej-Hulme, Marissa L., Jonkman, Inge, Janssen, Nico A. F., Rother, Nils, de Graaf, Mark, Pickkers, Peter, Kox, Matthijs, Joosten, Leo A. B., Nijenhuis, Tom, Netea, Mihai G., Hilbrands, Luuk, van de Veerdonk, Frank L., Duivenvoorden, Raphaël, de Mast, Quirijn, van der Vlag, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573491/
https://www.ncbi.nlm.nih.gov/pubmed/33123154
http://dx.doi.org/10.3389/fimmu.2020.575047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573491/
https://www.ncbi.nlm.nih.gov/pubmed/33123154
http://dx.doi.org/10.3389/fimmu.2020.575047

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