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Stromal Expression of the Core Clock Gene Period 2 Is Essential for Tumor Initiation and Metastatic Colonization

The circadian clock regulates diverse physiological processes by maintaining a 24-h gene expression pattern. Genetic and environmental cues that disrupt normal clock rhythms can lead to cancer, yet the extent to which this effect is controlled by the cancer cells versus non-malignant cells in the tu...

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Detalles Bibliográficos
Autores principales: Shaashua, Lee, Mayer, Shimrit, Lior, Chen, Lavon, Hagar, Novoselsky, Alexander, Scherz-Shouval, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573548/
https://www.ncbi.nlm.nih.gov/pubmed/33123539
http://dx.doi.org/10.3389/fcell.2020.587697