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Interaction of Alpha-Synuclein With Lipids: Mitochondrial Cardiolipin as a Critical Player in the Pathogenesis of Parkinson’s Disease

Alpha-Synuclein (α-Syn) is a central protein in the pathogenesis of synucleinopathies, a group of neurodegenerative disorders including Parkinson’s disease (PD). Although its role in neurotransmission is well established, the precise role of this protein in disease pathogenesis is still not fully un...

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Detalles Bibliográficos
Autores principales: Gilmozzi, Valentina, Gentile, Giovanna, Castelo Rueda, Maria Paulina, Hicks, Andrew A., Pramstaller, Peter P., Zanon, Alessandra, Lévesque, Martin, Pichler, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573567/
https://www.ncbi.nlm.nih.gov/pubmed/33122994
http://dx.doi.org/10.3389/fnins.2020.578993