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Inhibition of N-linked Glycosylation by Tunicamycin May Contribute to The Treatment of SARS-CoV-2

SARS-CoV-2 remains a medical and economic challenge, due to the lack of a suitable drug or vaccine. The glycans in some proteins play a pivotal role in protein folding, oligomerization, quality control, sorting, and transport so the hindering of N-linked glycosylation of glycoproteins will prevent a...

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Detalles Bibliográficos
Autores principales: Dawood, Ali Adel, Altobje, Mahmood Abduljabar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573633/
https://www.ncbi.nlm.nih.gov/pubmed/33091582
http://dx.doi.org/10.1016/j.micpath.2020.104586