Cargando…
Efficacy and mechanism of combination of oxaliplatin with PKM2 knockdown in colorectal cancer
M2 isomer of pyruvate kinase (PKM2), a key enzyme in aerobic glycolysis, is closely related to cancer development and progression. Suppression of PKM2 exhibits synergistic effects with docetaxel in lung cancer, but the therapeutic potential in colorectal cancer (CRC) is unclear. The aim of the prese...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7573921/ https://www.ncbi.nlm.nih.gov/pubmed/33093921 http://dx.doi.org/10.3892/ol.2020.12175 |